For the 10th weekend rally in a row, tens of thousands of protesters opposing long-time President Alexander Lukashenko marched through the capital despite threats of force from authorities to open fire.
Protesters were heard chanting "Strike!" and "You and your riot police get out!"
Crowds of demonstrators waved red-and-white opposition flags, marching through Minsk amid a heavy security presence.
"There's no way back," protester Anzhela Krasovskaya told a news agency. "If they start shooting then there would be even more people in the streets," she added.
Over 200 protesters were arrested during Sunday's protests, Belarusian Interior Ministry spokeswoman Olga Chemodanova told a news agency, adding that most of the detentions were in Minsk.
Water cannon and rubber bullets
Images from social media showed security forces deploying water cannon and blockading streets with barbed wire and heavy machinery.
A local media reported that security forces fired rubber bullets into the air in response to demonstrators throwing stones.
An Interior Ministry spokesperson later confirmed the reports, telling a news agency the rubber bullets were fired as a warning to protesters who threw stones at police.
Minsk authorities have also shut down a number of underground metro stations as well and decreased mobile internet coverage in an attempt to limit protests.
Over two months of protests
Demonstrators in the former Soviet republic have been demanding Lukashenko's resignation for weeks.
After more than two decades in power, Lukashenko claimed another round of victory in the country's August 9 elections over popular opposition candidate Sviatlana Tsikhanouskaya.
Tsikhanouskaya, who fled to neighboring Lithuania after the vote, has called on Lukashenko to step down before October 25, warning he would otherwise face a nationwide general strike that would paralyze the country.
Ahead of Sunday's protest, Tsikhanouskaya urged Belarusians to continue their calls for justice.
"We will stop only when every political prisoner walks free, when members of law enforcement begin to defend the people, and rule of law and honest elections return to Belarus," she said.
Belarus security forces have so far arrested more than 13,000 people.